Medicinal Chemistry

C. Randall Clark, Ph.D. (University of Mississippi, 1973). Development of analytical methods for drugs and metabolites in biological samples using appropriate analytical techniques; quantitative structure-retention relationships in HPLC; development of derivatizing reagents to facilitate chromatographic analyses; synthesis and pharmacologic evaluation of potential anticonvulsant agents; studies of structural and stereochemical factors affecting the mechanism of drug action at the molecular level.

Jack DeRuiter, Ph.D. (Virginia Commonwealth University/MCV, 1982). Design, synthesis and biochemical evaluation of enzyme inhibitors; synthesis and chemical reactivity of potential chemotherapeutic agents; synthesis of novel heterocycles as potential medicinal agents.

Forrest T. Smith, Ph.D. (Virginia Commonwealth University/MCV, 1985) Development of synthetic methodology required for the synthesis of organic medicinal agents including antiarthritics and antineoplastics; natural product synthesis.

Pharmaceutics

Charlene McQueen, Ph.D.

Daniel L. Parsons, Ph.D. (University of Georgia, 1979) Evaluation of methods of studying ligand-protein interactions; development of statistical approaches to studying protein-drug interactions; studies of alterations of plasma protein binding of medicinal agents in the presence of perfluorochemical blood substitutes.

Jayachandra Babu Ramapuram, Ph.D. (Institute of Technology, Banaras Hindu University, 1998)Topical and transdermal delivery of drug molecules, dermato-toxicity, dermal metabolism of chemicals, drugs and pharmaceuticals. Design and formulation development of various dosage forms. Solid state characterization, stability and improvement of solubility and bioavailability of insoluble drugs. Protein and peptide stability characterization for drug delivery.

William R. Ravis, Ph.D. (University of Houston, 1977). Pharmacokinetic characterization of human and veterinary pharmaceuticals and endogenous substance development of solid dispersion dosage forms; studies intestinal absorption, metabolism and influencing factor evaluation of binding of basic drugs to plasma proteins.

Pharmacology - Toxicology

Muralikrishnan Dhanasekaran, M. Pharm., Ph.D. (Indian Institute of Chemical Biology, Jadavpur University, 1999) Study the etiology and pathophysiology of aging and neurodegenerative disorders using valid animal models. Investigate the pharmacological and protective effects of various synthetic and alternative medicines in aging and neurodegenerative disorders.

Vishnu Suppiramaniam, Ph.D. (Auburn University, 1993) Electrophysiological, biochemical and molecular approaches to understanding glutamate receptor channel behavior and effects of nootropic compounds. Use of artificial lipid bilayer models to determine the mechanism of cytolysis by viral glycoproteins and bacterial toxins.